PROFOL (propofol injection IP 1% w/v) by Baxter Pharma -
Is an intravenous general anesthetic and sedation drug for use in the induction and maintenance of anesthesia or sedation. Intravenous injection of a therapeutic dose of propofol induces anesthesia, with minimal excitation, usually within 40 seconds from the start of injection (the time for one arm-brain circulation). As with other rapidly acting intravenous anesthetic agents, the half-time of the blood-brain equilibration is approximately 1 minute to 3 minutes, accounting for the rate of induction of anesthesia. The mechanism of action, like all general anesthetics, is poorly understood. However, propofol is thought to produce its sedative/anesthetic effects by the positive modulation of the inhibitory function of the neurotransmitter GABA through the ligand-gated GABAA receptors.
PRINCIPAL DISPLAY PANEL — 5 x 10 mL Vial Label
10 mL (Packaged 5 vials per box of 10 mL each)
For Single Patient Use Only
Injectable Emulsion 10 mg/10 mL (10 mg/mL)
CONTAINS BENZYL ALCOHOL
SHAKE WELL BEFORE USING
Each mL (of emulsion) contains:
Propofol IP 10 mg
Soya-bean Oil IP
Water for injection IP: q.s.
Storage: Store below 25°C. Do not freeze.
Contains no antimicrobial agents. Each vial is for use in a single patient only. Discard unused portion.